Plutarch was of the view that he became disabled by means of an attempt on his life by Philip II's wife, Queen Olympias, who wanted to eliminate a possible rival to her son, Alexander, through the employment of pharmaka (drugs/spells); however, most modern authorities doubt the truth of this claim., both to protect his life and to prevent his use as a pawn in any prospective challenge for the throne.
He appears as one of the main characters in the novel Funeral Games by Mary Renault.
In Renault's version, the villainous Cassander slows down his advance on Macedonia to give Olympias enough time to kill Arrhidaeus and Eurydice.
An agreement was made at Triparadisus in Syria in 320 BC.
Eurydice moved deftly enough to achieve the removal of the first two designated regents, Peithon and Arrhidaeus, but was powerless to block the aspirations of Antipater, whose position proved too powerful, and the latter was made the new regent; Philip Arrhidaeus and Eurydice were forced to follow Antipater back to Macedonia.
Cassander reciprocated by leaving her in full control of the country when he left to campaign in Greece.