The findings and conclusions in this report are those of the author(s) and do not necessarily represent the official position of the Centers for Disease Control and Prevention. All authors discussed the results and commented on the manuscript.As of 2014, most HIV transmission in the United States occurred among men who had sex with men, with this population accounting for 67% of new cases and 83% of new cases among males over 12 years old.
Comparisons with more recent data reveal many of these insights to be unattainable without archival, full-genome sequences.
We also recovered the HIV-1 genome from the individual known as ‘Patient 0’ (ref.
It will be used to facilitate the licensing of this methodology.
A patent, ‘Methods and systems for RNA or DNA detection and sequencing’ (US patent application 62/325,320), has been filed with the United States Patent and Trademark Office.
HIV is transmitted by three main routes: sexual contact, significant exposure to infected body fluids or tissues, and from mother to child during pregnancy, delivery, or breastfeeding (known as vertical transmission).